play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives. The Bacterial Vaccines group within Early Vaccines and Immune Therapies at Astra Zeneca is developing new and innovative vaccines against bacterial pathogens.
We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're pioneering innovative research and exploring novel platforms to deliver vaccines against bacterial pathogens. We're industry-leading in bacteriology, immunology, protein engineering and translational science. We offer an outstanding and strong collaborative
network as part of the Astra Zeneca family. Astra Zeneca has a dynamic environment that champions collaboration and innovation. We attract top minds, and we nurture and build top talents.
The Senior Scientist is responsible for leading the efforts within a multidisciplinary research group to design and develop fermentation methods to optimize expression levels of recombinant vaccine antigens. This position will involve hands on fermentation work to develop, scale-up and characterize microbial culture processes for research and development of bacterial vaccine antigens. This position will support one or more projects and will be required to present, publish, and work with our intellectual
property team as a scientific leader. Experience: A successful candidate will be a well-grounded critical thinker with demonstrated ability to design and implement experiments to improve fermentation yields of engineered and wild-type bacteria to optimize expression of carbohydrate and recombinant vaccine antigens.
There is some flexibility in technical expertise for this position, but relevant experience is necessary in at least a few of the following areas: Special Skills/Abilities: Bacterial and eukaryotic culture and expression systems for carbohydrate and recombinant protein expression. Bacterial and eukaryotic culture in shake flask and scale-up into single use and re-useable bioreactors up to 10L.
Upstream process optimization to increase carbohydrate and recombinant protein expression in bacterial expression systems. Developing methods and SOPs for tech transfer from research to development Experience working on multidisciplinary project teams and supporting teams in a matrix management environment. Experience with bacterial bioconjugate vaccine expression is a plus. The candidate must be an effective oral and written communicator with a track record of quality publications. In addition, the individual must be dedicated to maintaining high laboratory standards, good record keeping, with high regard for quality and safety and must possess good organizational and interpersonal skills in a highly interactive multidisciplinary team-oriented environment.
Job Complexity: The candidate will work with minimal direction, is encouraged to be an independent problem solver, generate high quality and reproducible data and will be required report this data at departmental meeting and at project team meetings. Education: M. S. (5 -10 years post degree experience) or Ph D (3+ years post-degree experience) in microbiology, biochemistry, biochemical engineering, biotechnology or related scientific discipline.
M. S. (5 -10 years post degree experience) or Ph D (3+ years post-degree experience) in microbiology, biochemistry, biochemical engineering, biotechnology or related scientific discipline. Why Astra Zeneca? Make a significant impact to patients' lives around the globe. At Astra Zeneca, we 're dedicated to being a Great Place to Work, where you are empowered to push the boundaries of science and ignite your Entrepreneurial ambitious spirit. There's no better place to make a difference in medicine, patients, and society. An inclusive culture that champions diversity and teamwork.
Always committed to lifelong learning, growth, and development. Where can I find out more? Follow Astra Zeneca on Linked In/company/1603/Follow Astra Zeneca on Facebook/astrazenecacareers/Follow Astra Zeneca on Instagram/astrazeneca_careers/? hl=en Date Posted 01-Sep-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be.
We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. All qualified applicants will receive consideration for employment without regard to race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a medical/ biomedical company, all while maintaining full-time benefits.
Essential Functions: The target client is a leading group responsible for the development of CHO based production cell lines, next-gen cell line engineering efforts and baseline upstream process development for innovative recombinant protein/adjuvanted vaccine projects and platforms. The target client is looking for a motivated professional, specialized in early in-process analytics, protein vaccines. This role will play a
significant role in shaping current and next generation leading vaccine platforms to accelerate addressing unmet medical needs, an exciting field having a direct impact into patients and global health.
This role provides the opportunity to integrate a diverse group of top talented experts in vaccines' industry, lead key activities and further grow and progress in your career. Main core responsibilities : 1. Development and implementation of in-process analytical methods (content, potency and process- and product-related impurities) to support cell line and early process development projects as well as next-gen cell line engineering. 2. Key team players to interact with the discovery and
preclinical teams and collaborate proactively to support antigen selection and early product understanding workflows to enable swift CMC onboarding.3.
Implement platform dd PCR and NGS based methods for testing cell line genetic stability and support next-gen cell line engineering effort. At PPD, part of Thermo Fisher Scientific we hire the best, develop ourselves and each other, and recognize the power of being one team. We offer continued career advancement opportunities, award winning training and benefits focused on the health and wellbeing of our employees. To learn how PPD, part of Thermo Fisher Scientific can advance your career, apply now! Education and Experience: Bachelor's degree or equivalent and relevant formal academic / vocational qualification Previous industry experience that provides the knowledge, skills, and abilities to perform the job: Scientist: With a bachelor's degree comparable to 2+ years of experience In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills and Abilities: Basic Qualifications: 1+ year hands-on solid experience with implementation of state-of-art multiplex immuno analytics, e.
g. ELISA, Octet, Biacore, Luminex and MSD for complex protein or biologics characterization. Hands-on experience with molecular analytics, e. g. real-time PCR or digital droplet PCR Preferred Qualifications: Experience with designing and implementing in-process analytics for content, potency and impurity. Experience with Quality by Design with demonstrated capability to develop fit-for-purpose high throughput in process analytics to support cell line development and cell line engineering. Experience with advanced NGS and Omics-techniques for transgene copy number/integrity/structure variant characterization.
Advanced knowledge of structure biology and protein engineering. Working Environment: PPD, part of Thermo Fisher Scientific values the health and well being of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role: Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. Able to work upright and stationary and/or standing for typical working hours.
Able to lift and move objects up to 25 pounds. Able to work in non-traditional work environments. Able to use and learn standard office equipment and technology with proficiency. May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment.
Science Jobs are specialized career paths within the field of science that encompass a wide range of disciplines such as biology, chemistry, physics, environmental science, and more. These jobs often require a strong educational foundation and specialized training. Key features of science jobs include a focus on research and development, data analysis, and the practical application of scientific knowledge to solve real-world problems. Additionally, professionals in science jobs are typically engaged in expanding the frontiers of scientific understanding and contributing to technological and medical advancements. These roles can be found in academia, government agencies, private sector research labs, and industrial settings.
MD, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives. The early Vaccines and Immune Therapies department at Astra Zeneca is developing new and innovative vaccines against bacterial pathogens.
We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're pioneering innovative research and exploring novel platforms to deliver vaccines against viral and bacterial pathogens. We're industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part
of the Astra Zeneca family, as together we explore synergies between small and large molecules. Astra Zeneca has a dynamic environment that fosters collaboration and innovation.
We attract top minds and we nurture and build top talents. What You'll Do Design, develop, and implement in vitro and in vivo experiments to characterize and validate novel targets against bacterial pathogens. Essential For the Role: A Master's degree with 4-6 years of experience or Bachelor's degree with 6-10 years of equivalent experience in assay development, bacteriology, cell biology, and in-vivo work. A successful candidate will be a well-grounded critical thinker who can design and implement in vitro (bacterial
biofilm and cell attachment assays, bacteria functional activity assays such as serum bactericidal, opsonophagocytic killing and anti-cytotoxic assays) and in vivo studies (mouse lung infection, bacteremia) and correlate these activities to backss the potential efficacy of monoclonal antibodies against bacterial pathogens.
Broad and strong experience with relevant cellular and antibody-based immunological techniques to characterize and select anti-bacterial monoclonal antibodies (e. g. FACS, western blot, ELISA, bacterial culture, bacteria cell-based ELISA, surface and intra-cellular target staining for cytofluorimetry) is required. In vitro based assays to quantify pro-inflammatory mediators in animals (ELISA, Luminex and MSD platforms, cell-based assays) Experience in animal procedure (intraperitoneal, intranasal, intravenous injections), bacterial disease models (lung infection, bacteremia) The candidate must be an effective oral and written communicator with a demonstrable track record of quality publications.
In addition, the individual must be dedicated to maintaining high laboratory standards, good record keeping, with high regard to quality and safety and must possess good organizational and interpersonal skills in a highly interactive multidisciplinary team oriented environment.
Desireable for the role: Experience in molecular biology (e. g. bacteria mutagenesis, DNA manipulation and cloning, sequence analysis, plasmid vector design and construction) would be a plus. Why Astra Zeneca? At Astra Zeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being bold - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-medical company can be.
This means we're opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Interested? Come and join our journey. So, what's next! Apply today! Are you ready to bring new insights and fresh thinking to the table? Brilliant! We have one seat available, and we hope it's yours. To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience - it is the only way that our Recruiter and Hiring Manager can know that you feel qualified for this opportunity.
If you know someone who would be a great fit, please share this posting with them. Where can I find out more? Check out our landing page for more information on our BPD group careers. /bpd Our Social Media, Follow Astra Zeneca on Linked In /company/1603/Follow Astra Zeneca on Facebook /astrazenecacareers/Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Date Posted 29-Sep-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.
We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. All qualified applicants will receive consideration for employment without regard to race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status.
Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
Science Jobs refer to employment opportunities within the various fields of science, ranging from entry-level positions to advanced research and academic roles. Key features of these jobs often include conducting experiments, data analysis, problem-solving, and innovation in sectors like biology, chemistry, physics, and environmental science. Science Jobs demand a strong educational background and typically offer the potential for contributing to technological advancements and understanding of the natural world. These positions are pivotal in driving scientific progress and can be found in laboratories, universities, and industry settings.
Science Jobs refers to a category of employment that specializes in the field of science, encompassing a diverse range of professions including researchers, laboratory technicians, science educators, and many others engaged in scientific disciplines. These jobs are characterized by their focus on inquiry, exploration, and the application of scientific methods to understand the natural world. They often require a strong educational background in science, critical thinking, problem-solving skills, and sometimes, experience with specialized equipment or software. In today's world, Science Jobs are crucial for innovation, technological advancement, and addressing complex challenges in healthcare, environment, and industry.
Science jobs refer to employment opportunities within the fields of science, encompassing a wide range of disciplines such as chemistry, physics, biology, and environmental science, among others. These jobs are characterized by their focus on research, data analysis, and application of the scientific method to investigate natural phenomena or to develop new technologies. Individuals in science jobs often work in laboratories, universities, research institutions, or within the private sector. They are crucial for the advancement of knowledge, innovation, and the practical application of scientific discoveries to improve various aspects of life and solve complex problems.
Science Jobs refer to employment opportunities within the various fields of science, such as biology, chemistry, physics, and environmental science. These positions often require a strong educational background in their respective disciplines and can range from academic research and teaching roles to industry-based positions in pharmaceuticals, technology, and more. Unique features of Science Jobs include a focus on innovation, evidence-based analysis, and the exploration of the natural world. They contribute significantly to technological advancements and the betterment of society through scientific discovery and application.
Science Jobs refers to a category of employment that specializes in the field of science, encompassing a diverse range of professions including researchers, laboratory technicians, science educators, and many others engaged in scientific disciplines. These jobs are characterized by their focus on inquiry, exploration, and the application of scientific methods to understand the natural world. They often require a strong educational background in science, critical thinking, problem-solving skills, and sometimes, experience with specialized equipment or software. In today's world, Science Jobs are crucial for innovation, technological advancement, and addressing complex challenges in healthcare, environment, and industry.
Science Jobs are specialized career paths within the field of science that encompass a wide range of disciplines such as biology, chemistry, physics, environmental science, and more. These jobs often require a strong educational foundation and specialized training. Key features of science jobs include a focus on research and development, data analysis, and the practical application of scientific knowledge to solve real-world problems. Additionally, professionals in science jobs are typically engaged in expanding the frontiers of scientific understanding and contributing to technological and medical advancements. These roles can be found in academia, government agencies, private sector research labs, and industrial settings.
Science Jobs is an employment niche focused on job opportunities within the science sector. It encompasses a diverse range of positions from research and development, lab work, to academic and corporate roles in various scientific disciplines like biology, chemistry, physics, and environmental science. The key feature of Science Jobs is its specialized nature, catering to individuals with a strong background in science and a passion for research and innovation. It provides a platform for employers to find highly-skilled professionals and for job-seekers to find roles that match their expertise. Science Jobs often requires candidates to have a specific set of qualifications, including advanced degrees and relevant experience, thus ensuring a highly qualified workforce driving scientific progress.
Science Jobs refer to employment opportunities within the various fields of science, such as biology, chemistry, physics, and environmental science. These positions often require a strong educational background in their respective disciplines and can range from academic research and teaching roles to industry-based positions in pharmaceuticals, technology, and more. Unique features of Science Jobs include a focus on innovation, evidence-based analysis, and the exploration of the natural world. They contribute significantly to technological advancements and the betterment of society through scientific discovery and application.
Science Jobs is an employment niche focused on job opportunities within the science sector. It encompasses a diverse range of positions from research and development, lab work, to academic and corporate roles in various scientific disciplines like biology, chemistry, physics, and environmental science. The key feature of Science Jobs is its specialized nature, catering to individuals with a strong background in science and a passion for research and innovation. It provides a platform for employers to find highly-skilled professionals and for job-seekers to find roles that match their expertise. Science Jobs often requires candidates to have a specific set of qualifications, including advanced degrees and relevant experience, thus ensuring a highly qualified workforce driving scientific progress.
Science jobs refer to employment opportunities within the fields of science, encompassing a wide range of disciplines such as chemistry, physics, biology, and environmental science, among others. These jobs are characterized by their focus on research, data analysis, and application of the scientific method to investigate natural phenomena or to develop new technologies. Individuals in science jobs often work in laboratories, universities, research institutions, or within the private sector. They are crucial for the advancement of knowledge, innovation, and the practical application of scientific discoveries to improve various aspects of life and solve complex problems.
Science Jobs refer to employment opportunities within the various fields of science, such as biology, chemistry, physics, and environmental science. These positions often require a strong educational background in their respective disciplines and can range from academic research and teaching roles to industry-based positions in pharmaceuticals, technology, and more. Unique features of Science Jobs include a focus on innovation, evidence-based analysis, and the exploration of the natural world. They contribute significantly to technological advancements and the betterment of society through scientific discovery and application.
