Location: Rockville
Company: Thermo Fisher
provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a medical/ biomedical company, all while maintaining full-time benefits.
Essential Functions: The target client is a leading group responsible for the development of CHO based production cell lines, next-gen cell line engineering efforts and baseline upstream process development for innovative recombinant protein/adjuvanted vaccine projects and platforms. The target client is looking for a motivated professional, specialized in early in-process analytics, protein vaccines. This role will play a
significant role in shaping current and next generation leading vaccine platforms to accelerate addressing unmet medical needs, an exciting field having a direct impact into patients and global health.
This role provides the opportunity to integrate a diverse group of top talented experts in vaccines' industry, lead key activities and further grow and progress in your career. Main core responsibilities : 1. Development and implementation of in-process analytical methods (content, potency and process- and product-related impurities) to support cell line and early process development projects as well as next-gen cell line engineering. 2. Key team players to interact with the discovery and
preclinical teams and collaborate proactively to support antigen selection and early product understanding workflows to enable swift CMC onboarding.3.
Implement platform dd PCR and NGS based methods for testing cell line genetic stability and support next-gen cell line engineering effort. At PPD, part of Thermo Fisher Scientific we hire the best, develop ourselves and each other, and recognize the power of being one team. We offer continued career advancement opportunities, award winning training and benefits focused on the health and wellbeing of our employees. To learn how PPD, part of Thermo Fisher Scientific can advance your career, apply now! Education and Experience: Bachelor's degree or equivalent and relevant formal academic / vocational qualification Previous industry experience that provides the knowledge, skills, and abilities to perform the job: Scientist: With a bachelor's degree comparable to 2+ years of experience In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills and Abilities: Basic Qualifications: 1+ year hands-on solid experience with implementation of state-of-art multiplex immuno analytics, e.
g. ELISA, Octet, Biacore, Luminex and MSD for complex protein or biologics characterization. Hands-on experience with molecular analytics, e. g. real-time PCR or digital droplet PCR Preferred Qualifications: Experience with designing and implementing in-process analytics for content, potency and impurity. Experience with Quality by Design with demonstrated capability to develop fit-for-purpose high throughput in process analytics to support cell line development and cell line engineering. Experience with advanced NGS and Omics-techniques for transgene copy number/integrity/structure variant characterization.
Advanced knowledge of structure biology and protein engineering. Working Environment: PPD, part of Thermo Fisher Scientific values the health and well being of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role: Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. Able to work upright and stationary and/or standing for typical working hours.
Able to lift and move objects up to 25 pounds. Able to work in non-traditional work environments. Able to use and learn standard office equipment and technology with proficiency. May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment.
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