DUTIES Lead molecular diagnostic assay development in a hands-on manner through successful FDA submission Manage and contribute to regulatory documents Project management; personnel management skills preferred Design assay performance specifications Ensure assay development process meets milestones and timelines Troubleshoot and solve technical issues Maintain compliant laboratory documents and procedures Pro-actively improve efficiency, quality and effectiveness of R & D efforts QUALIFICATIONS Ph D in Nucleic Acids Biochemistry, Molecular Biology, or related field Minimum of 7 years of relevant industry experience and IVD assay development In depth knowledge and hands on experience with q PCR,
sequencing and standard molecular biology techniques Demonstrated technical, managerial and leadership expertise in assay development Strong understanding of FDA and global regulatory requirements Demonstrated experience and understanding of quality systems (e.
g. GLP, ISO, etc. ) Prefer experience working in BSL-2 laboratory facilities Strong work ethic and ability to generate high quality work under tight deadlines Flexibility in work schedule Self-motivated, independent and a driving force of efficient execution Strong organizational and project management skills Excellent oral and written communication skills Job Posted by Applicant Pro
analyses and tests, and the appropriate preparation data; providing technical direction to technicians and laboratory support personnel by reviewing and confirming the results of routine tests, and providing instruction to assure conformity to SOPs; performing minor troubleshooting, maintenance and calibration duties on a variety of standard instrumentation and instructs or oversees technicians in their performance of routine equipment maintenance duties; maintaining current knowledge of analytical procedures and equipment; following SOPs to maintain accurate reliable data, and to affect the efficient transfer of the data to the LIMS and or other data management systems; utilizing standard applications
software and prepares accurate statistical and graphics displays, as instructed.
This position requires a bachelor's degree in chemistry or a related field and one (1) year of experience in chemical analysis, quality control and statistical techniques.
A valid Massachusetts Class D Motor Vehicle Operators Licenseis required. Internal applicants should apply using the Pipeline and external applicants should apply through . Massachusetts Water Resources Authority (MWRA) is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, national or ethnic origin, age, religion, disability, interaction or gender, interactionual orientation, gender identity or expression, genetics, or veteran status. Job Posted by Applicant Pro
position to support development of cell-based models of ALS and implementation of chemical and genetic screens for drug target and therapeutic discovery. Job responsibilities include generation of novel induced pluripotent stem cell-based models of ALS for use in in cellular phenotype discovery, screening assay development, and screen automation.
The successful candidate will be a highly motivated, detail-oriented individual with strong interest in biomedical research RESPONSIBILITIES: Generate i PSC-based models of ALS using patient-derived fibroblasts and genome edited cell lines Perform neural differentiations to generate cells for phenotype discovery Design, implement, and oversee
experiments Analyze and present data to the Cell Biology team and company-wide meetings Proactively review the scientific field to identify and share new scientific findings, ideas, and methods with other researchers REPORTS TO: Director of Cell Biology WORK LOCATION: Watertown, MA, 02472 WORK SCHEDULE: This position is full-time, Monday to Friday, 9-5 pm (with occasional short weekend shifts depending on ongoing cell work) QUALIFICATIONS: MS/MA or Ph.
D. in Molecular and Cell Biology or a related discipline, with mammalian cell culture experience. Must have at least 3-5 years experience Experience with general molecular and cellular biology techniques. Neurobiology, stem cell biology,
cellular immunology, genome editing, cell-based assay development, lab automation or high content cell analysis experience will be a plus.
Solid teamwork, reliability and ability to work on more than one project under supervision as well as independently. Excellent organizational and communication skills are a must. Job Posted by Applicant Pro
Digitalents is a two-year program that gives you the opportunity to complete different assignments while working with professionals from all over the world. You'll be part of a cohort, a community of talents, that will receive personalized guidance and support to help build the foundation for your future career.
From empowering group learning and development experiences around the world to expert career advice, you'll work alongside and have exposure with senior leaders who are invested in your success. About the role: We are seeking a motivated scientist to join our team working on Spatial Omics, RNASeq and digital Biomarker datasets, and Machine Learning applied to the analysis of biomedical
data. The ideal candidate should have a background and interest in data science, artificial intelligence, bioinformatics, biomedical engineering, or computational biology.
As a computational Scientist, you will have the opportunity to work on two assignments based in two separate locations: first year in Cambridge (USA) and the second year in Frankfurt (Germany). Main responsibilities as Computational Scientist: Perform biomedical image analysis Conduct genomics data analysis Conduct single cell RNASeq analysis Develop scalable analysis pipelines Implement machine learning models for solving biomedical problems Collaborate with other team members on various research projects Work with
large-scale datasets and employ machine learning techniques to solve complex problems About you : Strong knowledge of Python Familiarity with R is a plus Solid statistical and mathematical knowledge Understanding of methods in bioinformatics/computational biology Excellent analytical and problem-solving skills Ability to work independently as well as in a team environment Strong written and verbal communication skills Advanced English level Prior experience with biomedical data analysis is a plus but not required Molecular biology knowledge is a plus but not required Please mind that o nly applications submitted in English will be considered.
Note: this role is a VIE opportunity and is only available to European citizens due to external regulations.
Target start date: May 2024 Pursue progress, discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, interaction, national origin, interactionual orientation, age, citizenship, marital status, disability, or gender identity.
Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at ! #digitalents At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
Digitalents Graduate Program - Computational Scientist At Sanofi, we advance the process from discovery to therapy with the power of digital. We don't settle for less, and we hope you don't either. Digitalents is your opportunity to make a real impact on the transformation of our business and people's lives across the globe. Why Digitalents? Digitalents is a two-year program that gives you the opportunity to complete different assignments while working with professionals from all over the world. You'll be part of a cohort, a community of talents, that will receive personalized guidance and support to help build the foundation for your future career.
From empowering group learning and development experiences around the world to expert career advice, you'll work alongside and have exposure with senior leaders who are invested in your success. About the role: We are seeking a motivated scientist to join our team working on Spatial Omics, RNASeq and digital Biomarker datasets, and Machine Learning applied to the analysis of biomedical data. The ideal candidate should have a background and interest in data science, artificial intelligence, bioinformatics, biomedical engineering, or computational biology.
As a computational Scientist, you will have the opportunity to work on two assignments based in two separate locations: first year in Cambridge (USA) and the second year in Frankfurt (Germany). Main responsibilities as Computational Scientist: Perform biomedical image analysis Conduct genomics data analysis Conduct single cell RNASeq analysis Develop scalable analysis pipelines Implement machine learning models for solving biomedical problems Collaborate with other team members on various research projects Work with large-scale datasets and employ machine learning techniques to solve complex problems About you : Strong knowledge of Python Familiarity with R is a plus Solid statistical and mathematical knowledge Understanding of methods in bioinformatics/computational biology Excellent analytical and problem-solving skills Ability to work independently as well as in a team environment Strong written and verbal communication skills Advanced English level Prior experience with biomedical data analysis is a plus but not required Molecular biology knowledge is a plus but not required Please mind that o nly applications submitted in English will be considered.
Note: this role is a VIE opportunity and is only available to European citizens due to external regulations. Target start date: May 2024 Pursue progress, discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, interaction, national origin, interactionual orientation, age, citizenship, marital status, disability, or gender identity.
Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at ! #digitalents At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all. PDN-9aede302-642e-4693-98eb-e7f6c6013615
and scientific aspects of development and validation of new assays including Gx P studies May have direct reports and work as a group leader As a team leader, oversee the project timelines and put the best efforts to increase productivity. May represents the company in the scientific conferences or participates in the sales meetings Work with management and QA to maintain and improve quality systems Provide leadership and training to assigned research staff Provide high-quality documentation of all lab-related activities, including, for example, assay batch record, sample inventory, etc.
Perform a QC function to review data and reports to ensure the accuracy of all laboratory-related
processes. Maintain regular communication with the study director and other project staff and become a point of contact to the client. Job Qualifications and Requirements: A minimum of a Bachelor's in a scientific field with 5+ years or an advanced degree (MS/Ph.
D. ) with at least 3 years of relevant experience. Experience with assay development and validation is required. Experience with ELISA, Western Blot, Luminex, and cell-based assays is critical. Strong experience with GLP and c GMP is required. Ability to quickly acquire new skills and craft creative solutions. Must be detail-oriented with the ability to multi-task and work as part of a team to complete projects with strong communication
skills. Relocation may be available. This Associate Scientist position earns a competitive salary , depending on experience.
We also offer a full suite of benefits to choose from, including medical, dental, vision, a health reimbursement account funded by the employer, a healthcare & dependent flexible spending account (FSA), a 401(k) plan, 100%-employer-paid voluntary life/AD&D insurance, and profit-sharing. If this sounds like the right opportunity in medical research and cell & gene therapy for you, apply today! Pharmaron Lab Services cares about our work community and offers a variety of benefits allowing employees the opportunity to customize a comprehensive benefits package that meets their personal needs.
Pharmaron Lab Services is proud to be an Equal Employment Opportunity and Affirmative Action employer.
by following policies, processes, and acting in a safe manner at all times. Segregate chemicals by hazard class, packing compatible materials in appropriate containers and preparing for transportation, completing necessary paperwork per job, conducting various facility inspections as required.
Collects hazardous and non-hazardous materials from various onsite locations and transports via push cart or company van to waste collection areas. Characterize materials. Follows proper placarding and load segregation requirements when loading hazardous materials. Develop good client relations by effectively communicating with customers. Directs Field Technicians/Drivers assisting with waste collection.
Maintain a log of waste stored in the waste area. Advise when supplies are to be ordered. Maintain good housekeeping in storage areas. Heritage believes that each employee makes a significant contribution to our success.
That contribution should not be limited by the assigned responsibilities. Therefore, this position description is designed to outline primary duties, qualifications and job scope, but not limit the incumbent nor the company to just the work identified. It is our expectation that each employee will offer his/her services wherever and whenever necessary to ensure the success of our endeavors. Education: High school diploma or its equivalent required. Four year college degree
(Science major preferred) or 2+ years Lab packing or environmental experience preferred.
Experience: Prior lab packing or environmental waste experience preferred. Knowledge and Abilities: This is a safety sensitive position. The ability to work in a constant state of alertness and in a safe manner is an essential function. Introductory knowledge of high hazard materials management backssment and cylinder handling. Good knowledge and understanding of all federal, state, and local laws and regulations pertaining to the Environmental Services Industry. Excellent interpersonal skills necessary to effectively communicate with internal and external contacts.
Regular and predictable attendance is an essential function of this job. Requirements: Due to potential exposure to atmospheres/waste/materials this position requires that you must be able to be clean shaven at all times to don a respirator for your protection. Must have a valid driver's license. Ability to pass Motor Vehicle Record search to company standards. A post offer drug screen will be required. EEO including disability/veteran
where you belong and can be the best version of yourself. If you're passionate about achieving goals, trying new things and making an impact every day, we want to hear from you! POSITION SUMMARY: We're looking for a Sr. Scientist (R&D Technical Services) experienced in the Food & Beverage industry to lead our R&D technicians, and support a diverse set of teams across the Enterprise through product technical services and R&D systems management.
This position is key to the operation of the R&D team and has significant impact on the maintenance of our portfolio of shelf stable and refrigerated juices, sparkling beverages and fruit-based spreads. WHAT YOU'LL DO: Serve as the R&D lead for
the qualification and approval of new sources for existing ingredients Provide technical support and address inquiries on existing specifications, ingredients or products from Procurement, Quality, Manufacturing or Sales Serve as the R&D lead for the management of our Product Lifecycle Management (PLM) Specification System Update existing or generate new specifications within the scope of the role (formula, finished product, ingredients, and analytical test methods) Troubleshoot and work within the R&D functions of the PLM system, provide support & training to the broader R&D team Lead projects aimed at optimizing and leveraging the R&D functions of the PLM system (streamlining, incorporation
of new businesses or processes) General oversight of the product development analytical lab and instruments Manage and coach the R&D technicians, ensuring performance, engagement and career development opportunities Manage the technicians resource calendar to ensure the appropriate support across all R&D May be asked to perform other tasks or handle other responsibilities, as needed WHO YOU ARE: An ideal candidate: Enjoys challenges and problem solving; is technically deep and curious Is detail oriented and fast learner Exhibits good written and oral communication, along with strong collaboration skills Has familiarity and ability to work within a database environment and to follow digital links to other systems Has familiarity with basic analytical instruments such as refractometers, titrators, and spectrophotometers Able to self-manage projects including excellent organizational and time management skills Is hands on, resourceful and decisive; seeks practical approaches with a bias for action to quickly solve problems SKILLS AND EXPERIENCE: REQUIRED Bachelor's Degree in Food Science, Chemistry, or closely related fields.
Master's preferred. Candidates should have at least 5-7 years of experience in a product Technical Service, R&D or Quality role in the Food & Beverage industry, with a focus on juice or beverages preferred Ability to work cross-functionally with collaboration experience including Procurement, Quality, and Manufacturing, among others Technical knowledge of ingredients, products and manufacturing processes of beverages or foods Problem-solving skills and experience dealing with ambiguity Able to manage multiple projects and complete work in a timely manner Proficient in Microsoft Office Must be able to travel based on project requirements (about 10%) PREFERRED Familiarity working with PLM systems Experience managing personnel Product Development experience for Food and Beverages WHAT YOU'LL ENJOY: Organization with a bold, clear purpose.
Authentic culture that supports working together to deliver results. Workplace where teams care about each other and your voice is heard. Core and voluntary benefits so you can choose the right recipe for you. 40 hours paid volunteering time off for all non-union exmployees Generous 401(k) plan with annual company match. Flexible schedules so you can balance your work life priorities. Learning and development opportunities with coaching. Safe and clean working environment.
Welch's believes that our differences make the difference, and we take pride in being an Equal Opportunity Employer Disability/Vets. Job Posted by Applicant Pro
communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Akouos is building a leading gene therapy company focused on hearing disorders.
We are a precision genetic medicine company dedicated to developing gene therapies with the potential to restore, improve, and preserve high-acuity physiologic hearing for individuals living with disabling hearing loss worldwide. Restoring, improving, and preserving high-acuity hearing is an area of high unmet need in medicine: 466 million people worldwide have disabling hearing loss, and there are no FDA-approved
therapies to address its underlying causes. Akouos was founded in 2016 by leaders in the fields of neurotology, genetics, inner ear drug delivery, and AAV gene therapy.
Listening is in our DNA. We believe the only way to achieve our ambitious goals is to engage as one team, listen to each other, and trust in ourselves and our science. The Target Discovery and Genetic Technology and Innovation teams are seeking a motivated and committed scientist, with deep experience in molecular biology, to contribute to the evaluation and development of AAV vectors for the treatment of genetic and acquired forms of hearing loss. A successful candidate will work independently and perform benchwork that
supports discovery efforts and contributes to IND-enabling studies.
The scope of work includes the design, execution, and analysis of in vitro and ex vivo experiments using novel AAV vectors, with an emphasis on Next-Generation Sequencing (NGS) studies, and the implementation of organizational methods to support everyday lab operations. The successful candidate will be self-motivated and creative, with a desire to succeed in a highly collaborative and fast-paced environment. Job Responsibilities: Execute in vitro and ex vivo nonclinical experiments for the development of genetic medicines for the inner ear, including the following: Design and conduct in vitro , ex vivo , and in vivo single-nuclei RNA-seq experiments including sample processing, implementing 10X Genomics workflows, library generation and Illumina sequencing.
Design, conduct, and analyze in vitro transfection and transduction experiments using clonal cell lines and/or primary cell lines and performing such readouts as cell-based assays, luminescence readouts, epifluorescent microscopy, flow cytometry, q PCR, and/or western blot. Maintain accurate and timely documentation of activities through meticulous lab notebook practices and contributions to reports. Analyze, interpret, and present data for experiments, with the ability to clearly communicate results in written and oral formats for team feedback.
Organize key lab operations including leading and executing coordinated orders of specialized materials and instruments, and generation and maintenance of databases for samples and reagents. Basic Qualifications: Bachelor's Degree and/or Master's Degree in cellular biology, molecular biology, virology, medicine, or related field with 7+ years of relevant laboratory work experience; biotech or medical industry experience preferred but not required. Additional Skills/Preferences: Extensive experience in sample processing and execution of NGS studies for bulk and single-cell RNA-Seq, including sample preparation, 10X Genomics platform, library preparation, and sequencing.
Experience with RNA analyses (q PCR) and protein analyses (western blot). Experience with mouse handling, mouse tissue harvest, and tissue handling. Demonstrated ability to function as a member of an interdisciplinary team and contribute within a highly collaborative and fast-paced environment. Exceptionally organized and detail oriented. Excellent computer skills and Microsoft Products proficiency (Outlook, Excel, Word, Power Point, etc.
) to support database tracking of key lab operations, including samples, and protocols. Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively " Lilly" ) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( xyz X@lists. ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process.
Any other correspondence will not receive a response. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, interactionual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities.
Learn more about all of our groups. #We Are Lilly
Science Jobs refers to a category of employment that specializes in the field of science, encompassing a diverse range of professions including researchers, laboratory technicians, science educators, and many others engaged in scientific disciplines. These jobs are characterized by their focus on inquiry, exploration, and the application of scientific methods to understand the natural world. They often require a strong educational background in science, critical thinking, problem-solving skills, and sometimes, experience with specialized equipment or software. In today's world, Science Jobs are crucial for innovation, technological advancement, and addressing complex challenges in healthcare, environment, and industry.
Physical Therapist/Clinician , you will be responsible for providing home and community based early intervention services to infants and toddlers who have or are at risk for developmental delays and their families in both their homes and community settings.
You will partner with parents/caregivers to ensure service delivery is individualized, meaningful for the family, and grounded in evidence-based practice. Through this collaborative process you ensure families’ priorities, needs, culture, and values are prioritized. Thom Child & Family Services offers competitive salaries and a comprehensive benefit package including, but not limited to: Flexible Schedules: FT, PT, Per Diem and family
hours Health and Dental Insurance, including Fitness Benefits and Wellness Incentive Program. Generous vacation Personal time Sick time (80 – 96 hours every year) Paid holiday (10-12 paid holidays) 403(b) with employer matching Section 125 flexible benefits plan (Medical and dependent care) Employer sponsored Long-term disability insurance.
Employer sponsored Life Insurance Employer sponsored Accidental Death and Dismemberment Insurance Productivity Bonus Plan Continuing education leave and paid conference fees. Paid professional license renewal fees. Clinical supervision, mentoring and team support. Mileage reimbursement Other optional benefits: Short-term Disability Insurance Accident
Insurance Cancer Insurance Position Responsibilities: Participate in multidisciplinary team backssments of client’s developmental status.
Provide direct services and activities developmentally appropriate for children 0-3 and their families. Participate in the development of Individual Family Service Plan (IFSP) with responsibility for identifying goals, objectives, and strategies related to the child’s development. Complete progress notes, reports, backssments, and correspondence as appropriate Provides individual and group intervention for infants and toddlers from birth to three years old who have developmental delays or who are at risk for delays in the areas of cognitive, adaptive behavior, social-emotional, self-care, fine motor, gross motor, and communication development.
backss family and child strengths/resources, concerns, and progress. Act as service coordinator for the family by scheduling, developing, implementing, monitoring, and evaluating the intervention plan for each family on caseload, ensuring that appropriate procedures and timelines are followed. Provides supportive professional assistance to families. Facilitate parent-child interactions to encourage child's development; assist families to act as advocates for their child.
Position Requirements: Current licensure as a Physical Therapist by the Massachusetts Board of Registration of Allied Health Professions Experience with infants, toddlers and families is preferred Knowledge of family systems and early childhood development. Ability to engage in meaningful, therapeutic relationships with children, parents/caregivers, and community partners. Commitment to delivering individualized and culturally humble services. Excellent written and verbal communication and organizational skills. Abide by all confidentiality and professional boundaries standards. Good computer skills as well as strong documentation skills.
Current driver’s license and reliable transportation. Bilingual/Bicultural a plus. NO PHONE CALLS OR RECRUITERS PLEASE Thom Child and Family Services is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, interaction, interactionual orientation, gender identity, national origin, disability, veteran status, familial status, domestic violence status, or any other status protected by law. PIba62684b For more details: jobs-search. org/physical-therapist_worcester-c434669/physical-therapist-early-intervention-worcester_i1970118324
commercialization of novel metallization chemistries and processes that deliver industry-leading solutions that enable enhanced performance and functionality. The Applications Leader will be responsible for leading a group of talented Scientists and Engineers focused on the development and successful implementation of our advanced metallization solutions.
This role requires close collaboration with Commercial, Marketing, and project management functions to successfully deliver market-leading technology solutions. Close customer engagement and product promotion is expected to secure successful product installations and confirm critical to market technical requirements. Qualifications Lead
and motivate a team of scientists and engineers, establish a culture of safety, trust and accountability while meeting the speed to market demands. Research and develop new products and processes and evaluate new opportunities/platforms.
Lead a project team through product ideation to successful commercialization. Gather insight from customers and end users on emerging industry technology trends to validate product development priorities. Recognize emerging trends by close collaboration with customers to validate new market opportunities and define critical deliverables for new products. backss new applications for our existing product portfolio. Understand metallization processes and
applications. Represent the business at technical trade shows and conferences and effectively promote new products, Du Pont capability, and identify emerging technology synergies Be motivated to learn new technology and communicate their understanding effectively to the organization and their team.
Actively manage multiple value chain customer engagements, while working alongside technical, marketing, and commercial partners. Support product development and customer troubleshooting as part of maintaining portfolio health. Requirements Ph D in chemistry, chemical engineering, materials science, or related field Masters degree with industry experience would be considered Strong background in problem solving, using multiple analytical procedures to identify and characterize product development barriers.
Previous people leadership experience is highly desirable. Effective verbal and written communication to team members and management on all aspects of program activity. Demonstrated ability to make clear, persuasive, concise, and well-organized oral presentations Highly motivated and self-directed individual with excellent interpersonal skills and the ability to interact with employees at all levels in the organization. Knowledge of metallization, electronic component manufacture, or experience in the design, fabrication, specification, or reliability of electronic components is preferred.
Experience with product commercialization framework (PCF) or other product development stage gate processes is highly desirable. Travel Expectations: Position may require up to 20% travel to customer facilities and international locations.
Astra Zeneca is a global, science-led, patient-focused biomedical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading medical companies.
At AZ, we're proud to have an exceptional workplace culture that encourages innovation and collaboration. Here, employees are empowered to express different perspectives - and made to feel valued, energized and rewarded for their ideas and creativity. AZ is a place where passionate people can immerse themselves in their work and make significant contributions to scientific excellence and medicines - does this describe
a place where you would like to work? At Astra Zeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.
We're passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life! Astra Zeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer and to ultimately eliminate cancer as a cause of death! What you'll do: We are seeking a computational
chemist for our Oncology medicinal chemistry department based in Waltham, Massachusetts.
The successful candidate will be a professional computational chemist, with a passion for drug discovery and ideally experience of working in drug discovery project teams within a biotech or medical setting. You will be working closely with an established, transnational team of computational chemists within Astra Zeneca working on oncology drug discovery projects across a range of modalities and will have access to innovative computational methods, such as our FEP and AI platforms, and excellent lead generation capabilities. Major Responsibilities: As a leading member of the medicinal chemistry design team, you will be responsible for: Setting and delivering on computational and medicinal chemistry strategies to impact project success at all stages from drug target identification through to clinical candidate nomination.
You will have accountability for setting the computational chemistry strategy, carrying out structure- and ligand-based design and data analysis, extracting insight from large proprietary structural biology and SAR data sets; your contributions to molecular design will be expected to result in inventorship on patent applications. You will work closely with scientists from other disciplines including structural biology, biophysics, ADME/DMPK and safety sciences as part of the wider drug discovery project team and will present your work regularly to peers and senior partners.
Depending on experience and interest, you might also function as the lead chemist for a drug discovery project. At Astra Zeneca, we value scientific innovation. Maintaining an awareness of the current state-of-the art, you will identify promising new computational methodologies or technologies that could benefit drug discovery and will develop and implement these through internal or external collaborations, sharing exemplary practice across Astra Zeneca.
You will be expected to publish your work regularly in high quality scientific journals and at national and international conferences. You'll have the opportunity to build academic collaborations and to supervise graduate scientists and postdocs, as well as to mentor colleagues. The scope for personal development is vast. Education, Qualifications, Skills and Experience: Requirements: Ph. D. degree in computational chemistry (or similar), ideally with greater than 5 years of experience working as a computational chemist on drug discovery projects in a medical or Biotech setting, or B.
Sc. /M. Sc with 10+ years of experience Broad experience in protein structure and dynamics, structure- and ligand-based design, data analysis and/or property prediction A passion for drug discovery and an excellent understanding of medicinal chemistry concepts Innovative problem-solver, with a track record of impacting drug project delivery Scientific and project impact exemplified by high quality scientific publications Strong oral and written communication skills, team-working and time-management skills Why Astra Zeneca?
At Astra Zeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-medical company can be. This means we're opening new ways to work, pioneering innovative methods and bringing unexpected teams together. Interested? Come and join our journey. Site Description: Our Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park Bio Hub, just west of the city center.
Our Bio Hub facility, is a bold new R&D initiative, which cultivates life science discoveries and the exchange of ideas. Here, we play host to some of the most ground breaking technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to crafting a culture of inclusion and collaboration.
With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers. Our Waltham site offers a variety of amenities to help book efficiency and help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, & full-service cafeteria. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while growing collaboration between teams and the greater research community. So, what's next?
A place built on courage, curiosity, and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take calculated risks that write the next chapter for our pipeline. If you are swift to action, confident to lead, willing to collaborate, and passionate about the possibilities, then we are keen to hear from you! Where can I find out more? Our Social Media, Follow Astra Zeneca on Linked In /company/1603/ Follow Astra Zeneca on Facebook /astrazenecacareers/ Follow Astra Zeneca on Instagram /astrazeneca_careers/? hl=en Next steps : Apply today, or connect with our Talent Acquisition Partner - Kayla Harris: /in/kayla-harris-8723ab13b/ for a confidential discussion to explore this opportunity further.
We are looking forward to hearing from you! Date Posted 13-Nov-2023 Closing Date Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e.
g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
We currently have an exciting opportunity for someone who has a passion for PKPD modeling and DMPK science, applied to Cancer biology, ideally with experience of working with large molecule drug projects to join our team. As a Senior Scientist Translational PKPD, you will have the opportunity to drive strategy and provide global leadership in PKPD science on Antibody drug conjugates and Radio immuno- conjugates.
Your day-to-day role is to provide projects with specialist modeling input into exploring the PK/PD/Efficacy in pre-clinical models, and using these models in order to iteratively build an understanding of the dose & schedule requirements for therapeutic intervention across different
patient populations as a single agent and combined with other agents. Accountabilities: Representing Translational PKPD group and providing overall scientific leadership for cross functional and external collaborations involving DMPK.
Exploring the effects on target and pathway to understand the requirements for efficacy and set a candidate drug target profile (CDTP). Predicting human dose and regimen together with providing input into exposure and pharmacodynamic (PD) biomarker based decision criteria for early clinical trials. Driving learning through back translation of early clinical exposure and PD data and providing prioritized future options for clinical testing. Leading and participating
in Oncology strategic scientific initiatives and continuous improvement projects by providing expert M&S knowledge.
Having a breadth of influence and impact across Astra Zeneca Clinical Pharmacology and externally within their discipline. Identifying, championing and developing new insights. Leading scientific discipline networks and acting as a focus for debate within the Astra Zeneca scientific community. Advising on and participating in the development of Discovery or Development strategies in PKPD. Managing student and Post Doc programmes. Leading external collaborative projects with academic or cross-pharma pre-competitive groups. Providing disciplinary scientific leadership and presenting work through patents, publications and lectures.
Requirements: Education: Ph D, Completing Ph D before start date of position (preferably February 2024), Masters with at least 3 years of experience, or equivalent degree in a field with a significant component of Modeling & Simulation, such as systems biology, quantitative pharmacology, pharmacometrics, chemical engineering, physics, medical sciences or applied mathematics. 0-4 years of experience in a subject area with a significant component of Modeling & Simulation, such as systems biology, quantitative pharmacology, pharmacometrics, chemical engineering, physics, medical sciences or applied mathematics.
Desirable Experience: Relevant industry experience in Modeling & Simulation, ideally in preclinical/translational setting with a focus on ADC or RIC, or a MS degree with proven industry experience. Experience in a project-facing role within medical R&D. Comprehensive understanding of DMPK and pharmacology/safety aspects of drug discovery and development with a strong publication record. Track record of supporting PK, PKPD and TKPD aspects of projects, with a delivery focus and ability to meet timelines to prespecified quality and cost.
Specialist in tools such as Win Non Lin/Phoenix NLME, Non Mem, Berkeley Madonna, MATLAB, and Sim CYP. Excellent interpersonal and communication skills coupled with strong influence and leadership skills. Providing disciplinary scientific leadership and presenting work through patents, publications and lectures. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions.
That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. At Astra Zeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science.
Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. Empowered to step up, we free ourselves from fear of failure to dig deep into the biology of complex diseases and make bold decisions. Celebrating our successes and failures along the way. Are you ready to embrace new and varied opportunities to develop and learn? Are you ready to be part of a team that makes a bigger impact on patients' lives?
If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. Apply now! Date Posted 06-Dec-2023 Closing Date 05-Feb-2024Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics (e.
g. race, color, religion, interaction, interactionual orientation, gender identity, national origin, disability or protected veteran status). We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
of progenitor cell populations that includes but is not limited to pre-Malignancy/Multiple Myeloma. These efforts will support the generation of compelling preclinical data packages with an opportunity to participate in a wide range of drug discovery projects and collaborate with scientists across multiple disciplines.
Astra Zeneca is a global, science-led, patient-focused biomedical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. We are more than one of the world's leading medical companies. Astra Zeneca has a multifaceted environment that cultivates collaboration and innovation. We attract
top minds, and we nurture and build talent. Within Hematology R&D, we are committed to advancing the science to deliver life-changing medicines to patients most in need.
With a combination-focused pipeline that exploits the power of multiple scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. This unit has responsibility for the value chain from discovery through to late-stage development,
enabling rapid acceleration of promising early-stage assets and life-cycle management programs.
Major Responsibilities-Lead efforts to identify and validate hematological targets with a focus on pre malignancy. Generation of suitable models including engineered cell lines and PDX ex vivo models Design and execution of in vivo/ in vitro studies to support the characterization and development of candidate molecules. Genetic manipulation of cells utilizing knockdown or knockout and overexpression of protein for target validation Capable of interrogating and hypothesis generation from single cell and other omic data. Analyze data and maintain clear experimental records.
Adept at managing multiple priorities in an efficient and organized manner. Using decision making, organizational and communications skills to effectively collaborate with biologist and other scientist from a variety of backgrounds. Documentation and presentation of data, findings and experimental conclusions at various meetings including project team and department meetings. Requirements-PHD in biochemistry, cell/molecular biology, genetics, pharmacology, or cancer biology with at least +5 years of experience; industry experience or academic leadership preferred with a commensurate publication record is required.
Familiarity with multiple assay platforms and technologies including single cell analysis. Knowledge and experience with hematological cancers (Multiple Myeloma and NHL). Proven track record of success within project teams, including the ability to prioritize, backss, and either continue or adapt projects. Excellent oral and written communication skillinteractioncellent interpersonal and collaborative skills, and the ability to work independently and effectively in a highly dynamic environment. Ability to build and execute a project plan with defined timelines.
Proven track record of technical proficiency and creativity in experimental design, and independent thinking to achieve short/long-term goals are preferred. Our Waltham, Massachusetts facility develops life changing small-molecule research in North America, with innovative laboratories at the Gatehouse Park Bio Hub, just west of the city center. Our Bio Hub facility, is a bold new R&D initiative, which fosters life science discoveries and the exchange of ideas. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science.
We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. With a shuttle bus to and from Alewife station, the location provides you the ability to work in the heart of one of the world's most vibrant research centers. Our Waltham site offers a variety of amenities help keep our employees happy and engaged. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams and the greater research community.
As Astra Zeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026. Find out more information here: Kendall Square Press Release Working at Astra Zeneca Here you'll have the chance to create a substantial difference to patients' lives! With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines - for the world's most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and crafting the patient ecosystem.
Next Steps? Apply now! Astra Zeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Date Posted 20-Dec-2023 Closing Date 19-Jan-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at Astra Zeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
ultra-wideband coherent lidar; and we have MIT LL digital pixel focal plane array technology to develop unique passive IR sensors. These systems leverage our Groups’ creativity; over the past decade, our staff have filed 25 technology disclosures and have been granted 12 patents.
Additionally, our group projects have won multiple R&D100 Awards, a prestigious innovation award honoring revolutionary ideas in science and technology. Our portfolio of programs spans smaller, high-risk, high-reward seedling studies and experiments that explore novel techniques and technologies to the fielding of larger, more mature systems that are designed, developed and integrated onto target platforms, such
as aircraft. We host world-class expertise in optical phenomenology, optical sensors, high-speed embedded processing, and data exploitation and visualization algorithms.
We are a diverse, dedicated and innovative Group looking for exceptional candidates to help us build the next generation of optical sensors. Position Description We are looking for a highly motivated individual with a strong background in experimental optics who is also adept in data analysis and modeling to help develop next generation advanced EO/IR systems. The individual is expected to participate in all aspects of technology development spanning design, modeling, laboratory testing, integration, field collection,
and data analysis. Requirements Doctorate in physics, electrical engineering or equivalent.
In lieu of a Doctorate, a Master's degree and 4+ years of experience will be considered. Experience in one or more of the following areas is desired: laser radar, optical remote sensing, non-linear optics, optical spectroscopy, or infrared system analysis, computational imaging/algorithm development Desired Skills Strong experimental and analytical/modeling skills; adept in statistical data analysis; willingness to travel and strong presentation skills desirable. #CJ For Benefits Information, click http: //hrweb. mit. edu/benefits Selected candidate will be subject to a pre-employment background investigation and must be able to obtain and maintain a Secret level Do D security clearance.
MIT Lincoln Laboratory is an Equal Employment Opportunity (EEO) employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, interaction, interactionual orientation, gender identity, national origin, age, veteran status, disability status, or genetic information; U. S. citizenship is required. Requisition ID: 40150
