Location: Framingham, MA
Company: Sanofi
collaborate very closely with our Genomic Medicine Bioprocess Analytics, Characterization and Analytical Development groups, based in Framingham and Waltham MA. The applicant must have strong industry experience in developing automated liquid handler methods for common DNA/RNA sample prep workflows on Hamilton and/or Tecan platforms.
The successful candidate should have working knowledge in integrating liquid handlers to analytical instrumentation via robotic arms and scheduler software. Key Responsibilities: Automate sample preparation methods for GMP release of AAV or lentivirus gene therapy drug products. Design and establish integrated platforms for end-to-end automation of workflows.
Develop and implement new automated methods and data solutions. Perform maintenance on robotic platforms. Present results in cross-functional meetings. Develops job aids, SOPs and JSAs for lab equipment.
Participate in CMC meetings as an automation representative for improving current and future analytical methods. Mentor junior lab members in all areas of laboratory automation. Basic Qualifications: Ph. D. in Molecular Biology, Biotechnology or related discipline degree with a minimum of 4 years or MS degree with a minimum of 6 years of relevant experience in the biotechnology/medical industry. Proven experience in developing and qualifying automated methods to support gene therapy drug
development. Working knowledge of liquid handlers. Experience with integrating instruments.
Experience with robotic systems and scheduling software. Experience with computational analysis of biological data using program languages (R, Python, MATLAB, etc.). Preferred Qualifications: Experience with gene therapy specific analytical methods. Ability to troubleshoot mechanical issues associated with liquid handlers. Experience in evaluating, developing and implementing new automation technologies. General working knowledge of common data science tools; Python, R, SQL/no-SQL databases, AWS, Docker, etc. Ability to write tools and scripts to automate repetitive tasks.
Familiarity with networking (TCP/IP), or Serial Communications Sanofi Inc. and its U. S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; interaction, gender, gender identity or expression; affectional or interactionual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
The Bioanalytics Automation lab, part of the Global CMC Development organization, uses robotic workstations and general-purpose programming languages to accelerate and streamline analytical workflows. The lab supports analytical groups responsible for drug development, from pre-candidate selection through commercialization. The incumbent will collaborate very closely with our Genomic Medicine Bioprocess Analytics, Characterization and Analytical Development groups, based in Framingham and Waltham MA. The applicant must have strong industry experience in developing automated liquid handler methods for common DNA/RNA sample prep workflows on Hamilton and/or Tecan platforms.
The successful candidate should have working knowledge in integrating liquid handlers to analytical instrumentation via robotic arms and scheduler software. Key Responsibilities: Automate sample preparation methods for GMP release of AAV or lentivirus gene therapy drug products. Design and establish integrated platforms for end-to-end automation of workflows. Develop and implement new automated methods and data solutions. Perform maintenance on robotic platforms. Present results in cross-functional meetings.
Develops job aids, SOPs and JSAs for lab equipment. Participate in CMC meetings as an automation representative for improving current and future analytical methods. Mentor junior lab members in all areas of laboratory automation. Basic Qualifications: Ph. D. in Molecular Biology, Biotechnology or related discipline degree with a minimum of 4 years or MS degree with a minimum of 6 years of relevant experience in the biotechnology/medical industry. Proven experience in developing and qualifying automated methods to support gene therapy drug development. Working knowledge of liquid handlers.
Experience with integrating instruments. Experience with robotic systems and scheduling software. Experience with computational analysis of biological data using program languages (R, Python, MATLAB, etc.). Preferred Qualifications: Experience with gene therapy specific analytical methods. Ability to troubleshoot mechanical issues associated with liquid handlers. Experience in evaluating, developing and implementing new automation technologies. General working knowledge of common data science tools; Python, R, SQL/no-SQL databases, AWS, Docker, etc. Ability to write tools and scripts to automate repetitive tasks.
Familiarity with networking (TCP/IP), or Serial Communications Sanofi Inc. and its U. S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; interaction, gender, gender identity or expression; affectional or interactionual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all. PDN-9ad5bf42-a439-4aac93cd7180d
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