Bioinformatics Scientist | Gaithersburg, MD

Analytics division is a group of experts from different disciplines including Data Science, Real World Evidence and Bioinformatics who are focused on applying their skills to advance and transform the drug discovery process at Astra Zeneca. We collaborate deeply across all therapeutic areas and work closely with our leading biologists, chemists to try and address how big data can accelerate our drug development pipelines.

In particular, this role will focus on collaborating with AZ's Biologics Engineering group who are developing and productionizing a transformational AI driven high throughput antibody discovery platform using Illumina NGS technology. If you want to have an impact on

transforming patients' lives by accelerating new medicines to patients, this may be the position for you! We are looking for a Bioinformatics Scientist to join our translational Bioinformatics team.

What You'll Do: Contribute to the development of an end-to-end data analysis capability as part of a cross-functional team Evaluation of new NGS technologies Work collaboratively with data and drug discovery scientists to establish primary and secondary analytics workflows on new systems for biologics discovery Support testing and verification of data management analyses and tools and pipelines in collaboration with AZ stakeholders Demonstrate effective communication to translate complex concepts

to non-experts in internal and external scientific meetings Contribute ideas and provide creative input to projects across multiple disease areas including respiratory, immunology, cardiovascular, renal, metabolism and neuroscience.

Remain at the cutting edge of bioinformatics. Essential for the Role: Ph D in bioinformatics or related field and 3+ years relevant experience Experience in using and analysing illumina NGS data Demonstrated ability to apply data analysis methods to large datasets Experience with Python Ability to explore novel bioinformatic approaches to improve sensitivity and specificity of NGS based workflows. Strong, professional communication skills and excellent attention to detail, capable of developing good working relationships with diverse individuals Experience working within a team environment Takes ownership of tasks and has a can do attitude Desirable for the Role: Experience in illumina workflows, in particular the primary analysis around going from raw images to fastq files Experience with R, bash or Rust programming languages Experience with Kubernetes cluster and associated software e.

g. kubeflow First-hand experience in the analysis and interpretation of large, complex datasets. Experience with create production quality code and software engineering techniques and practices.

e. g. version control, Jira, Agile, Scrum, code reviews etc. Familiarity with multiple R&D data types, especially as they relate to therapeutic area research. Capability of successfully managing multiple simultaneous projects Date Posted 20-Dec-2023 Closing Date 19-Jan-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at Astra Zeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics.

We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Astra Zeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.