(PAH) and other pulmonary vascular diseases. The Ke lab will dissect the critical role of pericytes during pulmonary vessel remodeling, by using a combination of cell-based models of angiogenesis (AJP 2014 PMID: 25447046), multiple novel inducible transgenic murine models (Circulation 2018 PMID: 30586764, Cir Res 2012 PMID: 23011394), genome sequencing analysis (AJRCCM 2014 PMID: 24702692, AJP 2016 PMID: 27456128), in addition to CRISPR gene editing toolkits, 3D spheroid models, precision-cut lung slicing technology, high-resolution deep tissue imaging and single-cell RNA-seq.
Our ultimate goal is to identify potential therapeutic targets that could be exploited for the development of
new drugs capable of preventing abnormal vessel remodeling and obliteration in PAH. Boston Children's Hospital is ranked the #1 pediatric hospital in the nation by U.
S. News and World Report. It is home to the world's largest pediatric research enterprise, the leading recipient of pediatric research funding from the National Institutes of Health, and the primary pediatric teaching hospital for Harvard Medical School. Who are we looking for: Postdoctoral Research Fellow: Highly motivated Ph. D. with a strong background in one or more of the following areas Cell/Molecular/Developmental Biology, Vascular Biology, Immunology, Rodent(Cre/flox mouse/rat) Genetics, and related biomedical science
fields are encouraged to apply. The candidate must also have enthusiasm, excellent critical thinking skills, a track-record of productivity as demonstrated by at least one first-author peer-reviewed publication, an ability to work well both independently and as part of a team, and proficiency in written and oral English communication.
Prior experience with right ventricular pressure measurements in rodents, confocal, primary cell culture, bioinformatics (Single-cell sequencing, Ch IP-seq) and data analysis, and CRISPR mediated genome editing would be an advantage. Research Assistant: Candidates with Bachelor's or Master's degree in Biomedical Sciences or related discipline, Animal handling are preferred; good attention to details, excellent verbal and written communication skills are prerequisite; experience with rodents, confocal, molecular/cell biology, bioinformatics would be an advantage.
What will we offer you: A successful candidate will have the opportunity to lead independent and cutting-edge research projects with a world-class research facility while obtaining valuable experience with the relevant technology that prepares well for future positions in academia or industry. We will also provide a customizable curriculum, individual career development/support, and interdisciplinary and collaborative research community.
To apply, please send 1)a cover letter with a brief statement of research experience and future proposed interests, 2)a detailed curriculum vitae to: Ke Yuan, Ph D FAHA Assistant Professor Department of Pediatrics Boston Children’s Hospital 300 Longwood Ave, Boston, MA 02115 t: -xyz X email:
(September – December) to help with a research project investigating the effects of evolution on the strength of species interactions in nectar-inhabiting microbial communities. The project duties will consist of: • Laboratory work, including but not limited to, autoclaving, preparation of growth media, sterile culture techniques, and microbial microcosm experiments.
• Students can expect opportunities for professional development from this research experience. This is a great opportunity for students without prior laboratory experience. All research will take place on Stanford Main Campus in the Bass Biology Building. Qualifications: No prior experience working in a laboratory and/or
conducting field research is necessary; all training will be included in the position. A positive attitude, enthusiasm to learn, and attention to detail are the most important qualities in potential applicants.
Training and supervision of the undergraduate research assistant will be provided primarily by a graduate student researcher overseeing the project. Requirements: Applicants should be available for the entire duration of the project between mid-September and December 2019 with flexible start/end dates. The student should expect to devote 5-15 hours per week to the project. Besides being able to work at least 4 consecutive hours at least once per week, scheduling can be flexible
based on students’ needs. Students must be eligible for Federal Work Study.
Support: Eligible students will receive financial support via Federal Work Study. Contact: Interested applicants should send their CV or resumé and statement of interest to and ne to apply is Friday, September 20th, 2019. Apply: app. /jobs/3039793
and to improve child school readiness.
Primary duties include: 1) Recruiting and enrolling all participants at two San Jose clinics, 2) Completing the literacy surveys and parent/child interaction backssments, 3) Assisting with qualitative data collection, and 4) Coordinating with participants and staff for all data entry and analysis.
The Pediatric Advocacy Program will train the RA to complete all of the listed duties and ensure they are prepared to fill their role. The RA will ideally have interest and experience working with underserved populations. The RA must be able to communicate and interact effectively in English and Spanish. This position requires a self-motivated,
self-directed, highly productive individual who is able to function both as an independent contributor, leader and team player. The RA will report directly to the Medical Director and the Program Director and be an integral part of the research team.
Qualifications Required: • Fluency in English and Spanish • Excellent oral and written communication skills • Superb organizational skills and exceptional attention to detail • Ability to work independently Desired: • College degree in related field • 1-2 years of experience in a health related field • Knowledge and experience of research methods (data collection, analysis, etc. ) • Experience working with children under the age of 5 • Experience working in a clinical setting Contact Janine Bruce ( ) for more information.
as well as randomized clinical trials with breast cancer patients. This position would appeal to those interested in cognitive function, insomnia, or cancer. We are looking for research assistants who will help with neuropsychological testing and scoring, MRI scanning, scheduling, filing, data entry, scanning paper files to digital copies, and other responsibilities.
We are looking for students who are very reliable, flexible, and eager to learn about cancer patients' cognitive and sleep domains as well as understanding the importance of the day-to-day grind in research. This is excellent preparation for doctoral training in medicine, neuroscience, public health, or health/clinical psychology.
We require a schedule of one, uninterrupted 6-hour shift a week between the hours of 9AM and 6PM on Mondays, Tuesdays, Wednesdays, or Thursdays, and a 3-Quarter minimum commitment, starting Fall Quarter of 2016.
Because our study visits with participants must accommodate the participants' schedules, our student RAs are expected to be flexible and sometimes help with study visits outside of their specified shifts. Successful candidates will begin training immediately. Interested students who can make the aforementioned time commitments should email Melissa Packer at with their cover letter and resume/CV.
in brain development. We take a holistic biopsychosocial approach to understanding and treating mood problems among youth that encompasses many aspects of childrens’ lives. We hope this multidisciplinary approach will lead to a greater understanding of how to treat mood problems and lead to happier and healthier youth.
Student Research Assistants would have the opportunity to do any combination of the following in the PEARL lab: 1. Participate in weekly Lab Meetings 2. Co-pilot MRI scans 3. Administer neurocognitive tests 4. Score and enter data into REDcap databases; for the detail-oriented, build datasets 5. Oversee Oral Glucose Tolerance Tests conducted by nurses in a lab 6. Collect
demographic data 7. Administer surveys 8. Possibly Freesurf MRI data for very detail-oriented students and if training offered in the same timeframe 9. Help with community outreach 10.
For highly motivated and dependable students, data analysis and/or work on posters or papers We ask that our students commit to at least 6 hours a week to our lab and commit to an entire school year. If you are able to do that and are interested in getting involved in the work done in our lab, please email your CV/resume and cover letter to Melissa Packer: more information about the lab and its director, Dr. Manpreet Singh, please visit med. stanford. edu/pedmood and med. stanford. edu/profiles/manpreet-singh
and also read the project descriptions below: Project Title: Risk and Resilience in Youth at Familial Risk for Mood Disorders Project Information: Have you ever come across people with mood problems who worry about passing on their struggles to their children?
What can we recommend that concerned parents and kids do in order to promote childhood resilience—to equip kids with tools to cope with life’s stressors in adaptive, healthy ways? Get involved in this study, and you will come to better understand why some children of parents with mood disorders do not go on to struggle with those issues while others do! The goal of this study is to discover factors that make youth either vulnerable or resilient to developing mood symptoms.
Children (8-17 years) of families with and without histories of Major Depressive Disorder and Bipolar Disorder participate in clinical interviews, cognitive tasks, MRIs, and blood/saliva tests. We are starting to follow up with families participating in the study over the next 2-5 years to track neural and behavioral markers of risk over time and see if we can base any clinical outcomes on these measures. Project Title: Neurodevelopmental Features of interactionual Dimorphism in Pediatric Psychopathology Project Information: Would you like to work on big data and develop new models of the brain?
Are you interested in looking at psychiatric illness through a developmental lens? For the analytically hungry, we have genetic, brain, behavioral, and cognitive data for numerous kids. One area that we seek to understand is why girls sometimes more frequently experience depression and anxiety while boys experience attention deficits and hyperactivity. Using data from 10,000 kids in the Philadelphia Neurodevelopmental Cohort, our team is conducting exciting analyses to discover how the brain’s structure and function might explain apparent differences between boys and girls.
Project Title: Arousal Induced by Medication Study (AIMS) Project Information: Have you ever come across parents who have children with mood issues and are debating whether or not to have them take medication for those issues? Ever curious about better understanding the potential risks versus benefits of prescribed antidepressant medication in youth? Or more generally, are you looking to gain expertise in conducting clinical drug trials? The goal of this multi-site trial is to evaluate the benefits and safety of antidepressant and psychotherapy treatment in teens who have a family history of Bipolar Disorder and therefore could be at risk specifically for antidepressant-related dysfunctional emotional arousal.
These youth complete behavioral, clinical, physiological, and genetic backssments, as well as MRI scans of the brain. Project Title: Measuring Overeating and Mood Effects on Neurobehaviors Thro Ugh Maturation: (MOMENTUM) Are you interested in better understanding mind and body interactions? This study aims to elucidate the relationship between mood and appetite. Youth 9-17 years old who are struggling to maintain a healthy weight and experiencing sad moods are invited to have an MRI scan at two time points over the course of two years to examine neural reward networks that are activated while the child plays a game in the scanner.
Participants are also clinically evaluated for insulin sensitivity and symptoms of depression at baseline, 6 months, and 24 months. Project Title: Janssen This is a NEW study that invites adolescents and young adults (15-25 years) who have a parent with a diagnosis of Bipolar Disorder (BD) to provide clinical, genetic, and other biological information at 6-month intervals over 24 months.
The goal of the study is to evaluate early risk markers that are targets for treatment with the overall goal of delaying or preventing the onset of bipolar disorder in at-risk youth.
Research & Development (R&D) jobs involve the innovation and creation of new products, services, or processes. These roles are typically found in industries like technology, pharmaceuticals, engineering, and biotechnology. R&D professionals work to solve complex problems, develop patents, and improve existing offerings. Key characteristics of R&D jobs include a strong focus on experimental work, critical thinking, a passion for discovery, and often a requirement for advanced technical or scientific education. R&D teams are strategic assets that drive growth and competitiveness for their organizations.
Research & Development (R&D) jobs are positions focused on creating new products, enhancing existing ones, or discovering new knowledge to advance technology. Individuals in these roles typically work for companies aiming to innovate and maintain competitiveness. Key characteristics of R&D jobs include problem-solving, creativity, a strong technical background, and the ability to work collaboratively. R&D professionals often engage in experimental testing, data analysis, and continuous learning to achieve breakthroughs in sciences, engineering, or other fields. The nature of these jobs is inherently dynamic, requiring adaptability and a forward-thinking mindset.
Research & Development (R&D) jobs are pivotal roles within companies or organizations focused on creating new products or improving existing ones through innovative processes. Individuals in these positions are tasked with exploring cutting-edge technologies, conducting experiments, and analyzing data to develop products that meet market needs or address specific challenges. A key feature of R&D jobs is the emphasis on creativity and problem-solving, as well as the ability to work in dynamic environments that are often at the forefront of technological advancement. R&D professionals must also be adaptable, persistent in the face of failure, and have a strong foundation in scientific or technical disciplines.
Research & Development (R&D) jobs involve creating new products or improving existing ones through innovative processes in a variety of industries such as technology, pharmaceuticals, engineering, and consumer goods. R&D professionals are typically highly educated and skilled in scientific research, product development, and problem-solving. They work to push the boundaries of knowledge, often in laboratory settings or in the field, and contribute directly to a company's growth and competitiveness by turning novel ideas into marketable solutions. Such roles demand creativity, technical expertise, and a forward-thinking mindset geared towards technological advancement and market trends.
Research and Development (R&D) jobs involve creating new products, improving existing ones, or developing innovative solutions and processes within various industries. The roles are typically characterized by a strong focus on innovation, problem-solving, and continuous learning, as individuals in R&D must keep abreast of cutting-edge technologies and scientific advancements. These positions can range from laboratory researchers, development engineers, to product developers, and are essential for companies looking to stay competitive by bringing novel ideas to market. R&D professionals often work in teams, engage in creative thinking, and are crucial in driving the future growth of their organizations.
Research & Development (R&D) jobs are positions focused on creating new products, enhancing existing ones, or discovering new knowledge to advance technology. Individuals in these roles typically work for companies aiming to innovate and maintain competitiveness. Key characteristics of R&D jobs include problem-solving, creativity, a strong technical background, and the ability to work collaboratively. R&D professionals often engage in experimental testing, data analysis, and continuous learning to achieve breakthroughs in sciences, engineering, or other fields. The nature of these jobs is inherently dynamic, requiring adaptability and a forward-thinking mindset.
Research & Development (R&D) jobs involve creating new products or improving existing ones through innovative processes in a variety of industries such as technology, pharmaceuticals, engineering, and consumer goods. R&D professionals are typically highly educated and skilled in scientific research, product development, and problem-solving. They work to push the boundaries of knowledge, often in laboratory settings or in the field, and contribute directly to a company's growth and competitiveness by turning novel ideas into marketable solutions. Such roles demand creativity, technical expertise, and a forward-thinking mindset geared towards technological advancement and market trends.
Research & Development (R&D) jobs involve the creation of new products, solutions, or knowledge, contributing to advancements in technology, science, and medicine. These roles are characterized by innovation, experimentation, and problem-solving. Professionals in R&D are often experts in their fields and work in a variety of settings, from laboratories and universities to corporate environments. They drive progress by designing experiments, gathering data, and developing prototypes to bring theoretical concepts into practical use. R&D is critical for industries seeking to maintain a competitive edge and to continuously improve their offerings.
Research & Development (R&D) jobs involve the creation of new knowledge, products, or processes through innovation and rigorous investigation. These roles are often found in sectors like pharmaceuticals, technology, manufacturing, and academics. Key features include data analysis, experimental design, prototyping, and intellectual property management. R&D professionals are typically highly educated and possess a strong background in their field of expertise. The overarching goal of R&D jobs is to drive progress, improve existing offerings, and maintain competitive advantage through cutting-edge solutions and discoveries.
Research & Development (R&D) jobs involve the creation of new products, solutions, or knowledge, contributing to advancements in technology, science, and medicine. These roles are characterized by innovation, experimentation, and problem-solving. Professionals in R&D are often experts in their fields and work in a variety of settings, from laboratories and universities to corporate environments. They drive progress by designing experiments, gathering data, and developing prototypes to bring theoretical concepts into practical use. R&D is critical for industries seeking to maintain a competitive edge and to continuously improve their offerings.
