Location: Philadelphia, PA
Company: Penn Medicine
Today at Penn Medicine, someone will make a breakthrough. Someone will heal a heart, deliver hopeful news, and give comfort and reassurance. Our employees shape our future each day. Are you living your life's work? Pathology Full Time - Day Shift The Genomic Variant Analyst performs initial review of genomic data and maintains knowledgebase for variant interpretation and reporting.
This position serves as the liaison between the diagnostic laboratory and the health care providers. This individual works with pathology to triage incoming samples. This individual also assists with tasks related to test reimbursement. The Genomic Variant Analyst will also educate staff, residents/fellows,
and students. General lab workflow: ---Follows all lab pre-analytical and post-analytical procedures covering sample triage and handling, data analysis, and preliminary review.
---Reviews NGS data and investigates and annotates new variants ---Triages all specimens to ensure adequacy for our testing. ---Accessions all specimens into LIM system(s) as necessary. ---Takes appropriate corrective action according to established procedures when data analysis deviates from acceptable level. Documents all corrective actions taken. Immediately notifies Manager or Director if unable to resolve test system problem. Ensures data is not reported until all corrective action has been taken and the pipeline
is performing within specifications. --- Quality management: --- Participates in proficiency testing ensuring it is performed in the same manner as clinical specimens.
--- At the Manager's discretion, maintains specified documents required for review by regulatory agencies. --- Billing: --- Works with billing department and insurance providers to maintain accurate billing information. --- Additional responsibilities: ---Manages clinician related discussions about the lab's results (e. g. Molecular Tumor Board, etc). ---Works with the rotating Fellows/Residents to interpret clinical NGS data and manage sample triage. ---Fields internal and external inquiries about lab and test related questions.
---Interacts with outside labs and institutions. ---Contributes to publications. ---Maintains professional certification and licensure, as appropriate ---Performs other duties and responsibilities as assigned by the Manager or Director. --- Performs duties in accordance with Penn Medicine and entity values, policies, and procedures --- Other duties as assigned to support the unit, department, entity, and health system organization. Master's Degree in Genetic Counseling, Human Genetics, or related fields, required. Ph. D. in Genetic Counseling, Human Genetics, or related fields, preferred.3+ years Previous experience working in a diagnostic laboratory, required.
Familiarity with oncology and next generation sequencing technology, preferred. Experience working with insurance providers, preferred. We believe that the best care for our patients starts with the best care for our employees. Our employee benefits programs help our employees get healthy and stay healthy. We offer a comprehensive compensation and benefits program that includes one of the finest prepaid tuition assistance programs in the region. Penn Medicine employees are actively engaged and committed to our mission.
Together we will continue to make medical advances that help people live longer, healthier lives. Live Your Life's Work We are an Equal Opportunity and Affirmative Action employer. Candidates are considered for employment without regard to race, ethnicity, color, interaction, interactionual orientation, gender identity, religion, national origin, ancestry, age, disability, marital status, familial status, genetic information, domestic or interactionual violence victim status, citizenship status, military status, status as a protected veteran or any other status protected by applicable law. #J-18808-Ljbffr
Biotech/pharmaceutical jobs are positions within the sector that focuses on applying biological and chemical principles to the development of drugs, therapies, and medical technologies. These roles often entail conducting research, developing new medications, ensuring quality control, and overseeing clinical trials. The field is characterized by its innovative nature, adherence to stringent regulatory standards, and its critical role in advancing healthcare and patient outcomes. Careers in this industry often require specialized education and training in fields like biology, chemistry, pharmacology, and can range from laboratory scientists to regulatory affairs managers.
or life science with some level of chemistry or chemical lab experience. Good interpersonal and communication skills to be able to work well in both self-managed and team environment Able to manage multiple projects simultaneously, meeting established deadlines Comfortable with safely working with hazardous materials Strong interest in hands-on work to ensure a good understanding of the products Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals Strong problem-solving and decision-making skills Possess excellent verbal and written communication skills Ability to write routine reports and correspondence Possess strong computer
skills and ability to interpret data and trends Responsibilities: With minimal guidance from supervision and within established procedures, the individual will conduct routine as well as complex research laboratory activities in support of the Client Global Innovation Center.
The incumbent will provide support to the Chemists / Engineers in the research and development process. Research may include assistance with information/data management activities and analysis of results. Assist in the design of experiments, conduct those experiments independently and collect, summarize, and present the resulting data Troubleshoot problems as they arise in the laboratory; collaborate with research
investigators when erroneous or unexpected results occur Identify and suggest improvements in methods Produce research experimental results, or information/data management results, or assemble and configure small/pilot scale equipment and control systems utilizing a variety of techniques Document findings and communicating results Make suggestions on path forward and contribute to formulating work plans and managing daily workflow Inspect and perform routine maintenance on equipment used to conduct experiments at the designated work location Maintain appropriate inventory of chemicals and/or supplies necessary for the completion of experiments at work location Maintain a safe working environment Preparation and evaluation of coating formulations including electro-coat, primer, topcoat and clear coat using mixing equipment and various spray equipment Accurately run and record test results for all coatings formulations Interpret and communicate test results using computer-based systems Document experimental test results using computer programs such as Word, Excel Safely handle, categorize, and dispose of chemicals on a routine basis Handle multiple tasks under strict time constraints
Today at Penn Medicine, someone will make a breakthrough. Someone will heal a heart, deliver hopeful news, and give comfort and reassurance. Our employees shape our future each day. Are you living your life's work? Center for Personalized Diagnostics The Genomic Variant Analyst II will be proficient using a variety of computational databases such as COSMIC, Onco KB, the UCSC genome browser, et al to aid in the interpretation of genomic variants.
The successful candidate will be familiar with concepts in molecular biology and genomics, meticulous with complex data review and documentation, possess strong critical thinking and organizational skills, and communicate effectively in a team-oriented
environment. The Genomic Variant Analyst demonstrates a thorough knowledge of Genomics Laboratory and Variant Analyst operations, including theoretical aspects of technical procedures, as well as department policies and routines with minimal technical supervision.
Responsibilities: Applies knowledge and skills to accurately follow all lab post-analytical procedures covering data analysis and preliminary review. Follows all lab pre-analytical, analytical and post-analytical procedures covering specimen, analytical test system and result reporting requirements. Reviews NGS data and investigates and annotates new variants. Takes appropriate corrective action according to established procedures
when data analysis deviates from acceptable level.
Documents all corrective actions taken. Immediately notifies Manager or Director if unable to resolve test system problems. Ensures data is not reported until all corrective action has been taken and the pipeline is performing within specifications Monitors, performs, and documents all Quality Control issues. Identifies issues/factors that adversely affect test performance. Provides analytical support to staff, physicians, and personnel to resolve any issues related to data analysis. Takes appropriate corrective action according to established procedures, when test system performance deviates from acceptable level.
Documents all corrective actions taken including calling technical support. Immediately notifies Supervisor and/or Director if unable to resolve test system issue. Ensures test results are not reported until all corrective action has been taken and test system is performing within specifications. Participates in Proficiency Testing and ensures proficiency testing is performed in the same manner as patient specimens. Maintains compliance with Proficiency Testing policies. As directed by the Manager, maintains and updates laboratory policies, procedure manuals and specified documents required for review by regulatory agencies.
Ensures that all employees are kept up to date with these changes. Assists the manager in specified activities that ensure laboratory compliance with all accreditation agencies. Compliance with Competency accreditation guidelines is a staff responsibility that must be completed annually. May function as the General Supervisor for selected duties when required. Demonstrates initiative in continually improving personal knowledge, skills, and work experience; and in improving departmental functioning. Works well with Manager and those in authority; works at establishing a good rapport and cooperative working relationship with all members of the laboratory; maintains a positive rapport with medical staff and hospital personnel.
Responsible for maintaining adequate staffing. As directed by the Manager, coordinates the training of new employees, rotating Fellows/Residents to interpret clinical NGS data and manage sample triage. Investigates laboratory incident reports and documents the findings as per UPHS procedures. Master of Arts or Science , required. Molecular biology, genetics, or related field 3+ years Genomic variant analysis in a Diagnostic Laboratory OR other genomic data analysis experience, required.
Possess the ability to perform tasks that require accurate and specific color distinction, required. We believe that the best care for our patients starts with the best care for our employees. Our employee benefits programs help our employees get healthy and stay healthy. We offer a comprehensive compensation and benefits program that includes one of the finest prepaid tuition assistance programs in the region. Penn Medicine employees are actively engaged and committed to our mission. Together we will continue to make medical advances that help people live longer, healthier lives.
Live Your Life's Work We are an Equal Opportunity and Affirmative Action employer. Candidates are considered for employment without regard to race, ethnicity, color, interaction, interactionual orientation, gender identity, religion, national origin, ancestry, age, disability, marital status, familial status, genetic information, domestic or interactionual violence victim status, citizenship status, military status, status as a protected veteran or any other status protected by applicable law. #J-18808-Ljbffr
opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America's Best Large Employers in 2023.
Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home
for work and play. The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.
Posted Job Title Bioinformatician A (Department of Pathology and Laboratory Medicine) Job Profile Title Bioinformatician A Job Description Summary The Yanxiang Deng Lab (yanxiangdenglab. org/) at the University of Pennsylvania Perelman School of Medicine is seeking a skilled and motivated bioinformatician to join our team to analyze
spatial omics datasets. This individual will be responsible for assuring the quality of sequencing data using existing tools, aggregating data into databases, creating relevant figures and statistical analyses on a per-project basis, and work with the lab members to submit sequencing data to publicly available repositories.
Additionally, this individual will create and document reusable software tools that can be used across multiple projects, and perform data analysis to find biological patterns in a wide range of genetic and epigenetic sequencing. The bioinformatician will also assist with employee training for routine data quality control, analysis, and visualization.
Finally, the bioinformatician will contribute to manuscripts, reports, and grant applications based on the biological significance of each dataset. Job Description Job Duties Additionally, this individual will create and document reusable software tools that can be used across multiple projects, and perform data analysis to find biological patterns in a wide range of genetic and epigenetic sequencing. The bioinformatician will also assist with employee training for routine data quality control, analysis, and visualization. Finally, the bioinformatician will contribute to manuscripts, reports, and grant applications based on the biological significance of each dataset.
This individual will be responsible for assuring the quality of sequencing data using existing tools, aggregating data into databases, creating relevant figures and statistical analyses on a per-project basis, and working with the lab members to submit sequencing data to publicly available repositories. Position contingent upon funding Qualifications Bachelor of Science and 3 to 4 years of experience or equivalent combination of education and experience is required. Job Location - City, State Philadelphia, Pennsylvania Department / School Perelman School of Medicine Pay Range $51,824.00 - $78,000.00 Annual Rate Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile.
Affirmative Action Statement Penn adheres to a policy that prohibits discrimination on the basis of race, color, interaction, interactionual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
Special Requirements Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job. University Benefits Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family's health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars. Tuition: Take advantage of Penn's exceptional tuition benefits.
You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions. Retirement: Penn offers generous retirement plans to help you save for your future. Penn's Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard. Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family-whatever your personal needs may be.
Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you're newly hired, you won't have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.
Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That's why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance. Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally. University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities.
Take advantage of the University's libraries and athletic facilities, or visit our arboretum and art galleries. There's always something going on at Penn, whether it's a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you're right in the middle of the excitement-and you and your family can enjoy many of these activities for free. Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff.
Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks. Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.
Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements. Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household. To learn more, please visit: www. hr. upenn. edu/Penn HR/benefits-pay
