Senior Scientist - Discovery Vaccine Bioanalytics
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Alabaster, AL
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Jun 22, 2023
will be responsible to contribute with limited supervision to all aspects of assay development, technology transfer, and/or troubleshooting. The ideal candidate will have solid laboratory experience in the field of immunology and/or cell biology, a broad skill set encompassing working with primary immune cells to developing bioanalytical assays capable to meet clinical assay requirement.
The candidate should be current on state-of-the art technologies and is expected to champion evaluation of new technologies and optimize processes. Providing expert technical representation on multidisciplinary teams will be expected. Responsibilities Provide scientific input to the design and execution
of ligand binding assays (LBA) such as ELISA and/or cell-based assays such as luciferase reporter assays Responsible for the execution of method development, troubleshooting and/or pre-clinical/clinical sample analysis as needed Contribute to the backssment and implementation of new analytical technologies Serve as an internal subject matter expert on developed assays Accountability for generated the data Work Experience Education Minimum Requirement: Ph D in Biological Sciences or related area with 0-3 years, or a MS degree with 4+ years, or a BS degree with 7+ years Required Skills: Critical thinking and good trouble-shooting skills Experience in general cell biology methods including maintenance
of cell lines and/or primary cells Experience with immunoassays such as ELISA, Alpha Lisa, multiplexed LBA on MSD and/or Luminex platforms Adherence to basic safety procedures in a BSL2 laboratory Good verbal and written communication Ability to follow procedures and thoroughly document experiments Communicate results effectively in presentations to stakeholders in partner organizations or at external scientific meetings, to write technical reports, and to participate on cross-functional teams Preferred Experience and Skills: Experience with cell-based assays in the context of immune response characterization such as viral neutralization, PRNT/VRNT/FRNT, ELISpot, or multi-color flow cytometry Prior experience with PBMC isolation, human and/or mouse tumor tissue processing Experience in molecular biology technique such as DNA and RNA isolation, q PCR, digital PCR, RNAseq, NGS, or CRISPR Familiarity with liquid handlers and other automation platforms for sample preparation and assay process Strong attention to detail with the ability to multi-task and handle multiple responsibilities simultaneously #PCDBio Analytical Requisition ID: P-100545PDN-9908367e-af45-44b8-bab7-c08c0a508d70
