Scientist, Translational PK/PD | Alabaster, AL

Johnson, and you can count on us to keep working tirelessly to make that future a reality for patients everywhere, by fighting sickness with science, improving access with ingenuity, and healing hopelessness with heart. We focus on areas of medicine where we can make the biggest difference: Cardiovascular & Metabolism, Immunology, Infectious Diseases & Vaccines, Neuroscience, Oncology, and Pulmonary Arterial Hypertension.

Visit us: . The Scientist will provide input into experimental design and highlight key uncertainties associated with their analyses and predictions. Modeling approaches used may include physiologically based pharmacokinetic modeling, mechanistic PK/PD modeling, and/or

systems pharmacology modeling to help (a) predict preclinical and clinical PK profiles (b) quantify exposure/response relationships for target engagement biomarkers, efficacy, and potential adverse effects, and (c) guide in vivo and in vitro experimental designs that will be most informative for modeling.

Key Responsibilities: Apply Pharmacokinetic/Pharmacodynamic (PK/PD) modeling to drive project team decisions from early discovery through early clinical studies. Contribute to guiding modeling and simulation strategies within the organization. Support discovery project teams and interact closely with biology, chemistry, and other drug metabolism and pharmacokinetic (DMPK) project

members to analyze experimental data to characterize dose- and exposure-response relationships and to predict effective doses for preclinical and clinical studies.

Education: Ph D in Pharmacology, Engineering, Mathematics, Physics, or related fields is required. Outstanding candidates with a Master's degrees and at least 2 years of relevant proven industry experience may also be considered. Experience and Skills: Familiarity with principles of pharmacokinetics and pharmacodynamics and experience performing PK and/or PK/PD modeling is preferred. Proven skills in mathematical modeling and simulation, supported by peer-reviewed publications is highly desired. Excellent interpersonal, organizational, oral/written communication and teamwork skills are required.

Other: This position may require up 10% travel. The anticipated base pay range for this position is $104,000 to $166,750. The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market. Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, interaction, interactionual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

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