Location: Lake County
Company: Abbvie
degrader compounds and drive drug discovery efforts for both platform and pipeline projects. You should be able to work independently while contributing to a team environment and manage several projects simultaneously. The successful candidate must stay current with applicable internal/external scientific literature and be able to analyze, document, and report data rigorously.
You should possess excellent communication skills and be proficient in presenting in front of groups. Join our team at Abbvie and contribute to ground-breaking research in the field of target protein degradation. Responsibilities: Independently conceive and execute rigorous scientific research to profile potency,
efficacy, and mechanism of action for degraders (including, but not limited to ternary complex formation and ubiquitination) utilizing plate-based biochemical/cellular assays and quantitative western blot Innovate by developing novel biochemical and cellular assays to support structure-activity relationship (SAR) studies for degraders Drive and contribute to pipeline projects in collaboration with Therapeutic Area and Platform biology leads.
Demonstrate a high level of initiative and proficiency in troubleshooting experiments and be an internal leader by example for high standards in data analysis and quality Maintain good written records of laboratory procedures and communicate research
findings in cross-functional project team meetings and publications.
Qualifications: Position will be filled at level commensurate with extent of education, experience, and accomplishments Scientist II: BS in Biochemistry, Biophysics, Molecular Biology, Cell Biology, or related field of Biological Sciences with typically 7+ years of experience or MS and typically 5+ years of experience Sr Scientist I: BS Biochemistry, Biophysics, Molecular Biology, Cell Biology, or related field of Biological Sciences with typically 10+ years of experience, MS and typically 8+ years of experience, or Ph D and typically 0+ years of experience Demonstrated track record of scientific achievement (publication/presentation record) Proven ability to develop, analyze, and interpret assays for interrogation of biological questions Proficiency in standard biochemical and/or cellular/molecular techniques such as TR-FRET, Alpha LISA, Western Blots, ELISA, and Nano BRET Expertise/background in ubiquitin proteasome system biology or targeted protein degradation preferred, but not required Experience in small molecule drug discovery in academia or industry preferred, but not required Excellent problem-solving and multi-tasking skills in a fast-paced environment Must be a team-player with strong oral and written communication skills Abb Vie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion.
It is Abb Vie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, interaction (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, interactionual orientation, marital status, status as a protected veteran, or any other legally protected group status.
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