Scientist (GPCR) - Protein Technologies Center | Memphis, TN

Here you can be part of a collaborative culture that will inspire you every day to be your best. Join us and you'll quickly learn why St. Jude is consistently ranked as one of The Commercial Appeal's Top Workplaces in the greater Memphis area. JOB SUMMARY : The Protein Technologies Center (PTC) in the Department of Structural Biology is seeking a highly motivated Scientist with experience in protein and membrane protein biochemistry to join a newly funded GPCR collaborative project to investigate the molecular determinants and fidelity of GPCR signaling in health and disease.

As part of the collaborative grant, the candidate will work closely with several partnering labs (Scott Blanchard,

Madan Babu, Robert Lefkowitz, Alice Ting, Jonathan Javitch, and Georgios Skiniotis). Successful candidates should have demonstrated competencies in the following areas: Cloning, expression, purification, and biochemically characterizing membrane proteins from mammalian and/or insect cell systems.

Prior experience with membrane protein or GPCR structural studies or functional assays. A significant contribution towards peer-reviewed research articles in the related scientific subject(s). Excellent record-keeping, communication, and presentation skills and ability to prepare high-quality manuscripts of findings for publication. Responsibilities: Design constructs, clone, express, and purify

GPCRs, G-proteins, arrestins, and other signaling proteins for structural, functional, and biophysical experiments to investigate structure-dynamics-function relationships.

Structure determination using either Cryo EM or x-ray methods. Work independently, leading a project from hypothesis to high-quality oral presentations and publications. Collaborate with an interdisciplinary group of researchers as part of a multi-institutional collaborative, including presentations to a broad audience. Train and mentor graduate students, post-docs, and visiting scientists. Instruct other staff in basic laboratory techniques and procedures. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required.

Ph. D. in molecular biology, biochemistry, protein engineering, or any related discipline preferred. Minimum Experience: Seven (7) years of relevant post-degree work experience is required with a Bachelor's degree. Five (5) years of relevant post-degree work experience is required with a Master's degree. Three (3) years of relevant post-degree work experience is required with a Ph D. Benefits: Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices.

We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Diversity, Equity and Inclusion: St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion.

Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St.

Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. Have More in Memphis: Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages.

Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can " Have More in Memphis. " Other Information St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St.

Jude.