Senior Scientist in Microbial Pathogenesis | Memphis, TN

Department will focus on fundamental research in the areas of antimicrobial resistance, host-microbe interactions, and immunity. A Senior Scientist position is available in the laboratory of Dr. Victor J. Torres , the chair of the Department of Host-Microbe Interactions at St.

Jude Children's Research Hospital. The Torres lab is interested in dissecting the complex interactions between pathogenic bacteria and the mammalian host. Currently, the lab is focusing on antibiotic resistant (AMR) bacteria, which have been recognized by the World Health Organization as a serious threat to human health. We take advantage of multidisciplinary approaches and combine techniques from bacteriology,

genetics, molecular biology, biochemistry, structural biology, cellular biology, and immunology with primary tissue culture models and a variety of murine models of infection, to address our favorite questions.

Our ultimate goal is to understand the basic principles of bacterial pathogenesis as well as to develop a platform for the discovery of targets that could be exploited for the generation of much-needed therapies. We are looking for an exceptional scientist to help us lead studies on the genetics, pathogenesis and mechanisms of immune evasion by AMR microbes. The individual is expected to lead projects that have both fundamental and translational components. A Ph D or equivalent,

and extensive postdoctoral research experience are required. Expertise in bacterial genetics, comparative genomics, host-pathogen interaction, protein structure, host response to infection, and/or mouse models is highly desirable.

Applicants should have a strong publication record, exceptional communication and organizational skills, willingness to work in a team atmosphere, willingness to train juniors scientists, and should have excellent multitasking abilities. Recent notable publications by the Torres lab include: Buckley PT et al. Cell Host & Microbe. 2023 Apr 20: S)00148-8; Lacey KA et al. Journal of Experimental Medicine. 2023 Jun 5;220(6): e20221086; Dyzenhaus S et al.

Cell Host & Microbe. 2023 Feb 8;31(2):228-242. e8; Zwack EE et al. Proceedings of the National Academy of Science. 2022 Aug 2;119(31): e2123017119; Zheng X et al. Nature Communications. 2021 Oct 26;12(1):6193; Perelman SS et al. Nature Microbiology. 2021 Jun;6(6):731-745; Tam K et al. Journal of Experimental Medicine. 2020 Sep 7;217(9): e20190541; Boguslawski KM et al. Science Advances. 2020 Mar 11;6(11): eaax7515; Keller MD et al. Nature. 2020 Mar;579(7798):260-264; Sause et al. Proceedings of the National Academy of Science. 2019 Jul 2;116(27):13563-13572St. Jude Children's Research Hospital is supported by ALSAC, one of the world's leading nonprofit charitable organizations.

ALSAC exists solely to raise and provide the funds necessary to operate and maintain St. Jude. Our unique funding model affords St. Jude researchers with excellent support, state-of-the-art facilities, resources, and a remarkable degree of freedom to innovate and pursue novel research questions impacting infectious diseases and other catastrophic diseases. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required Minimum Experience: Ten (10) years relevant post-degree work experience is required Eight (8) years of relevant post-degree work experience is required with a Master's degree Six (6) years of relevant post-degree work experience is required with a Ph D St.

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