Scientist / Senior Scientist Opportunity in St. Jude's Center for Advanced | Memphis, TN

facilities, state-of-the-art technologies, and extraordinary support for your research to ensure scientific progress is never halted from a lack of resources. At St. Jude, you will be part of a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve.

This is an exciting opportunity for a Scientist or Senior Scientist to join our Center for Advanced Genome Engineering (CAGE). The CAGE has three missions: 1) facilitate investigator-initiated genome editing projects using CRISPR-Cas9 2) perform independent R&D to evaluate and develop new genome editing techniques 3) to assist the gene and cell therapy programs

at St. Jude Children's Research Hospital. The Shondra Pruett-Miller laboratory offers a strong team-based environment where you will work collaboratively with other investigators across the institution to support their research needs and develop and improve genome engineering technologies.

In this position, you will lead the Custom CRISPR Library service. You will stay up to date on current CRISPR screening technologies and adapt and incorporate them into current workflows to aid St. Jude investigators with their research. Duties will also include designing, cloning, and analyzing CRISPR libraries designed for knockout, inhibition, and activation screens. You will help fellow team members

with their own designs and analyses. Your experience will also be used for developing and implementing bioinformatic workflows which aid CAGE lab members in CRISPR design and NGS analysis.

Successful candidates should display competencies in the following areas: Understanding of and experience with molecular biology techniques including DNA and RNA extractions, PCR, and plasmid cloning In depth knowledge and experience with CRISPR screens and analysis Excellent verbal and written communication skills Creative and self-motivated Experience with programming in python or other coding language is a plus Experience with liquid handling robots a plus Comfortable in a Linux environment and working on a cluster Comfortable working independently and as part of a team Ability to prioritize work based on need Ability to track and execute multiple projects at once Experience with Next-Generation Sequencing analysis is a plus Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required.

Minimum Experience: Scientist: Seven (7) years of relevant post-degree work experience is required with a Bachelor's degree. Five (5) years of relevant post-degree work experience is required with a Master's degree. Three (3) years of relevant post-degree work experience is required with a Ph D.

Senior Scientist: Five (10) years of relevant, post-degree work experience is required with a Bachelor's degree. Two (8) years of relevant post-degree work experience is required with a Master's degree. Three (6) years of relevant post-degree work experience is required with a Ph D. St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay.

Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.

Other Information St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.